Cellular Senescence in Microglia as a Contribution to Neurodegenerative Conditions (opens in new tab)

Increasing attention in the research community is being given to age-related dysfunction of microglia in the brain as a contribution to loss of cognitive function and onset and progression of neurodegenerative conditions. Microglia are innate immune cells analogous to macrophages elsewhere in the body, responsible not just for defense against pathogens, but also maintenance of neural tissue and supporting the function of neural networks. With age a growing population of microglia become senes...