Disruption of the Integrator Responsible for RNA 3′ End Processing Slows Aging in Nematodes (opens in new tab)

Researchers have established a number of interventions in short-lived species that extend life as a result of degrading the function of a cellular component, usually the mitochondria. Some forms of degraded function induce the cell to increase maintenance activities and otherwise alter its behavior to produce a net benefit to function, resistance to damage, and other line items that combine to reduce the level of age-related dysfunction in tissues and thereby extend life span. Where alteratio...