Evidence for Sleep Apnea to Accelerate Vascular Aging via Increased Cellular Senescence (opens in new tab)

Sleep apnea is correlated with cardiovascular disease, among other conditions. It induces a state of hypoxia in tissues when regular breathing is interrupted. Here, researchers induce a similar degree, duration, and intermittency of hypoxia in mice to examine the effects it has on vascular tissue. They find that this sort of hypoxia exposure increases the burden of senescent cells in the vasculature, alongside worsened measures of cardiovascular dysfunction. The researchers further show that ...