Examining the Extracellular Matrix of Skin in Long-Lived Naked Mole-Rats (opens in new tab)

Naked mole-rats live very much longer than other similarly sized rodents, and exhibit very little age-related decline until very late life. Researchers use this species as a point of comparison to attempt to better understand mechanisms of aging that might be targeted in mice and humans. Here, for example, the focus is on naked mole-rat skin structure. As is the case for other organs, old naked mole-rat skin doesn't exhibit the evident signs of aging observed in old mice and humans. Why is th...