BMAL1 as a Potential Lever to Influence Macrophage Behavior (opens in new tab)

Macrophages are innate immune cells found throughout the body, important not just for their ability to defend against infectious pathogens, but also deeply involved in tissue maintenance and regeneration. Macrophages can adopt different packages of behaviors - known as polarizations - in response to circumstances. The simple model, which likely glosses over many lesser differences that are important in some contexts, divides the macrophage population into M1 and M2 polarizations, distinguishe...