There are Multiple Distinct Approaches to Metabolic Adjustment for Greater Longevity (opens in new tab)

Adjusting the operation of metabolism to modestly slow aging has long formed the bulk of fundamental research into intervention in aging. All living organisms exhibit some plasticity of life span when subject to mild stresses, such as lack of nutrients, heat, cold, and so forth. Unfortunately this strategy seems unlikely to lead to therapies that greatly improve upon the effects of exercise and lifestyle choice, particularly given the evidence for metabolic adjustment to produce ever smaller ...