ApoB and LDL partially explain the association between family history of diabetes and lower clinical pregnancy in women who conceived with PCOS (opens in new tab)

PurposeTo investigate whether family history of diabetes (FHD) is associated with reproductive outcomes in women with polycystic ovary syndrome (PCOS), and to explore whether baseline metabolic biomarkers statistically explain part of this association.Materials and methodsWe performed a secondary analysis of the PCOSAct trial. Outcomes were first summarized in the full trial cohort, and the primary post-conception analysis was then restricted to the 320 women who conceived. Modified Poisson r...