Frontiers

Effects of hesperidin supplementation on inflammation and oxidative stress in overweight or obese individuals: a systematic review and meta-analysis of randomiz... (opens in new tab)

This study aimed to evaluate, through a systematic review and meta-analysis of randomized controlled trials (RCTs), the effects of hesperidin and hesperidin-containing citrus interventions on biomarkers of inflammation, oxidative stress, and endothelial function in overweight or obese individuals. Two authors independently searched PubMed, Web of Science, Embase, Scopus, and the Cochrane Library from inception to April 4, 2026. Methodological quality was assessed using the Cochrane Risk of Bi...

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