ITGA5 is overexpressed and promotes tumor progression through SNAI2 in OSCC (opens in new tab)

Integrin subunit α5 (ITGA5) has been recognized as a potential diagnostic biomarker across multiple cancer types. ITGA5 is upregulated in head and neck squamous cell carcinoma (HNSCC). Oral squamous cell carcinoma (OSCC), with poor prognosis and high mortality, accounts for two-thirds of HNSCC cases. However, the biological functions and underlying mechanisms of ITGA5 in OSCC progression remain unclear. In the present study, we analyzed the expression, prognostic significance, function, and c...