Targeted autophagy: research progress on the regulatory potential of periodontitis prevention and treatment (opens in new tab)

Chronic periodontitis is a multifactorial inflammatory disease primarily caused by bacterial pathogens, leading to progressive destruction of both soft and hard periodontal tissues. While dental plaque biofilm has been universally recognized as the primary etiological factor in periodontitis development, disease progression is also influenced by local irritants and systemic modulators, making its pathogenesis complex and widely studied. Autophagy, an essential cellular self-protection mechani...