Development of Rapid Multiplex Human Herpesvirus (HHVs) Detection Systems Based on Recombinase Polymerase Amplification (RPA) and a Lateral Flow Assay (LFA) (opens in new tab)

Human herpesviruses (HHVs) are highly prevalent globally (e.g., Epstein-Barr virus with over 95% prevalence) and can persist latently for life, causing severe conditions like blindness, encephalitis, and even lethal infections in neonates. HHV reactivation is of particular clinical concern in transplantation medicine, where immunosuppression can trigger viral reactivation, leading to graft rejection, secondary infections, and increased mortality. Notably, latently infected cells show no patho...