A novel cyp26c1-driven reporter line to study boundaries of retinoic acid signalling during zebrafish development (opens in new tab)

Retinoic acid (RA) signalling is essential for vertebrate development, but the spatiotemporal dynamics of its regulation remain largely uncharacterized in specific cellular contexts. Here, we introduce a novel gene trap transgenic reporter line for the zebrafish cyp26c1 gene, a key regulator of RA metabolism. Through a screen of a gal4-based gene and enhancer trap collection, we isolated the tg(gSAIGFF104A) line. In this line, a gal4 gene trap cassette is inserted into the third intron of the...