Deciphering the cellular landscape and genetic underpinnings of fiber diameter determined by dermal papilla cells in fine-wool sheep (opens in new tab)

Wool fiber diameter (FD) is a key economic trait in fine-wool sheep, and its growth process is closely associated with the development and cyclical growth of hair follicles (HFs). Therefore, a comprehensive understanding of the molecular mechanisms regulating HF development is of significant importance. In this study, single-cell RNA sequencing (scRNA-seq) was performed on skin tissues from six half-sibling fine-wool sheep reared under identical conditions but exhibiting different fiber diame...