Detection and prognostic role of circulating cancer-associated fibroblasts in the blood of melanoma patients (opens in new tab)

BackgroundCancer-associated fibroblasts (CAFs), frequently present in many tumor tissues, have received increasing attention over the past decade, while research on CAFs circulating in the blood of cancer patients is still in its infancy. This is the first study to assess the incidence, concentration, and potential prognostic value of cCAFs alone or in combination with other biomarkers such as circulating tumor cells (CTCs) or cancer-associated proteins, in melanoma patients.MethodsCTCs and c...