Identification of the key immune and inflammatory related gene CALCRL as diagnostic biomarker in differentiating uterine leiomyosarcoma from leiomyoma (opens in new tab)

BackgroundUterine leiomyosarcoma (ULMS) is a highly malignant tumor with a poor prognosis. This study aims to explore the potential and significance of novel immune and inflammation-related diagnostic biomarkers in differentiating ULMS from uterine leiomyomas (ULM).MethodsWe analyzed 25 samples of ULMS and 25 samples of ULM from the GEO database (GSE64763). Differentially expressed genes (DEGs) were identified using R software. Different Inflammation- and immunity-related genes (DIIRGs) were ...