Development and clinical validation of a nursing risk prediction model for chemotherapy-induced febrile neutropenia in patients with cancer (opens in new tab)

BackgroundFebrile neutropenia (FN) is one of the most serious yet potentially preventable complications of systemic chemotherapy. However, practical tools that support nursing-led early risk stratification and workflow-ready preventive actions remain limited.MethodsWe performed a real-world cohort study including 2,125 patients with cancer receiving systemic chemotherapy at a single institution. Patients were randomly split (7:3) into a derivation cohort (70%) and an internal validation cohor...