Insights gained from single-cell sequencing analysis of ischemic stroke (opens in new tab)

Ischemic stroke represents a significant global health hazard, causing substantial morbidity, mortality, and long-term disability worldwide. The brain’s complexity necessitates targeting ischemic stroke dysfunction syndrome. Single-cell RNA sequencing (scRNA-seq) offers unbiased, high-resolution analysis of cell heterogeneity, revealing cellular markers and types. Limited therapeutic options and drug discovery hinder stroke treatment, but scRNA-seq provides insights into new targets and bioma...