Frontiers

Optimal strategies for umbilical cord mesenchymal stem cell–derived exosomes in acute kidney injury: a network meta-analysis in rat models (opens in new tab)

BackgroundExosomes derived from umbilical cord mesenchymal stem cells (UCMSC-Exos) have emerged as a highly promising cell-free therapeutic strategy for repairing acute kidney injury (AKI). However, preclinical evidence regarding their efficacy and optimal administration strategy remains heterogeneous and has not been systematically synthesized.MethodsPubMed, Web of Science, Embase, and Scopus were systematically searched to identify randomized controlled experiments evaluating UCMSC-Exos in ...

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