AI-enabled multi-omics integration in colorectal cancer: from molecular stratification to clinical translation (opens in new tab)

Colorectal cancer (CRC) remains a heterogeneous disease for which improved molecular stratification is needed across the clinical pathway. Multi-omics technologies have expanded insight into CRC biology, and artificial intelligence (AI) has created new possibilities for integrating molecular, pathological, imaging, and clinical data. This review examines how these approaches are being applied across screening, diagnosis, treatment, and prognosis, with particular emphasis on their clinical rel...