Piezo1 ion channel: a core target for mechanotransduction in orthodontic alveolar bone remodeling (opens in new tab)

Physiological tooth movement during the process of orofacial rehabilitation, as well as the degree of skeletal responses to orthodontics procedures, depends on the bone remodeling processes that are controlled by the mechanosensitive receptors. Piezo1 has become one of the receptors of great attention over the last few years. Besides acting as a sensor of the mechanical microenvironment, Piezo1 is also important in alveolar bone remodeling because of its ability to regulate osteocyte activity...