Coconut oil/lauric acid-based nanodrug formulation: a multifunctional platform for enhancing cancer therapy and mitigating toxicity (opens in new tab)

The significant toxicity associated with anticancer drugs during traditional treatments, such as surgery, radiation, chemotherapy, and hormonal therapy, limits their therapeutic index by causing various adverse effects on healthy cells. Particularly, the clinical application of platinum (Pt)-based anticancer drugs (Pt-ADs), including cisplatin, carboplatin, and others, is challenging and severely hampered by intrinsic drug resistance, oxidative stress, and toxicity. Lipid-based nanodrug deliv...