Follicular fluid-derived exosomal LINC02701 promotes granulosa cell apoptosis through the GRP75–P53 axis in active endometriosis (opens in new tab)

BackgroundEndometriosis (EMs)-associated infertility has been linked to alterations in the follicular microenvironment; however, the role of exosomal long non-coding RNAs (lncRNAs) in granulosa cell dysfunction remains incompletely understood.MethodsFollicular fluid-derived exosomes were isolated from patients with active endometriosis (EMs_A), controlled endometriosis (EMs_C), and non-endometriosis controls. Transcriptomic sequencing was performed to identify differentially expressed exosoma...