Integrated analysis of cell-in-cell related genes and immune microenvironment in heart failure (opens in new tab)

BackgroundHeart failure (HF) is a major global public health challenge, and its pathogenesis involves the regulation of a complex immune microenvironment (IME). Cell-in-cell (CIC), as a non-classical form of cell-cell interaction, has been extensively studied in fields like oncology, but its role in HF remains unclear. This study aimed to systematically analyze the expression patterns and functions of CIC-related genes (CRGs) within the HF immune microenvironment.MethodsBased on transcriptomi...