Broccoli-derived nanovesicles protect against UVB-induced skin photoaging via integrated transcriptomic and proteomic reprogramming of redox and extracellular matrix homeostasis (opens in new tab)

Ultraviolet B (UVB) radiation is a major environmental factor driving skin photoaging by disrupting redox balance, activating inflammatory cascades, and accelerating extracellular matrix (ECM) degradation. Although plant-derived nanovesicles have emerged as promising bioactive delivery systems, their regulatory mechanisms in skin homeostasis remain incompletely understood. Here, we investigated the protective effects and molecular mechanisms of broccoli-derived nanovesicles (BDNVs) against UV...