Regenerative potential of CD200- subpopulations of hair follicle bulge (opens in new tab)

The hair follicle bulge is regarded as a reservoir of epithelial stem cells for hair regeneration. Hair follicle bulge cells are generally characterized by CD200 expression. However, the relationship between CD200+ bulge subpopulations and human hair regenerative capacity remains unknown. In this study, we systematically investigated the CD200- and KRT15-expressing human hair follicle bulge cells by integrating phenotypic characterization, transcriptomic profiling, and in vivo hair regenerati...