Identification of common genes associated with diabetic nephropathy and diabetic retinopathy (opens in new tab)

BackgroundThere is a common basis of the diabetic nephropathy (DN) and diabetic retinopathy (DR), but the common genes of DN and DR were unclear.MethodsIn this study, DN-related and DR-related transcriptome data GSE185011 was extracted. Firstly, the differentially expressed genes 1 (DEGs1) between DN and normal control (HC) samples, and DEGs2 between DR and HC samples were screened by “limma”. Then, the common genes of DN and DR were obtained by intersecting the DEGs1 and DEGs2. Next, the enr...