Decoding Rho GTPase signalling networks in directed cell migration (opens in new tab)

Small G proteins are molecular switches in the realm of cell biology, switching from the GTP-bound active form to the GDP-bound inactive form. They participate in controlling various essential cellular functions, one of which is cell migration. Cell migration is a sine qua non for the proper functioning of the cell, as it aids in a litany of cellular processes, including embryonic development, morphogenesis, organogenesis, wound healing, and pathogenic states such as cancer metastasis. Amongs...