Adipose-derived mesenchymal stromal cell-microenvironment interaction network in metabolic syndrome: ADMSC injury response, adaptive regulation, and regenerative potential (opens in new tab)

Metabolic syndrome (MetS) is a complex metabolic disorder characterized by insulin resistance, central obesity, dyslipidemia, hypertension, and chronic inflammation, which collectively increase the risk of type 2 diabetes mellitus, cardiovascular disease, and metabolic dysfunction-associated steatotic liver disease. Although adipose-derived mesenchymal stromal cells (ADMSCs) have shown promising therapeutic potential in preclinical studies, their efficacy is substantially influenced by the di...