Unraveling Let-7f in oncology: a tumor suppressor with emerging clinical significance (opens in new tab)

As a major global health threat, tumors present significant clinical challenges due to their heterogeneity, metastatic potential, and therapy resistance. In recent years, non-coding RNAs, particularly microRNAs (miRNAs), have emerged as crucial players in cancer research. Among them, let-7f, a key member of the let-7 family, exhibits significant dysregulation and biological functions in various cancers. This review systematically summarizes the differential expression patterns of let-7f in co...