Insights into oncovirus-driven tumor dynamics: a perspective from intravital imaging (opens in new tab)

The tumor microenvironment (TME) is a critical determinant of cancer initiation, progression, and therapeutic response. It comprises not only tumor cells but also immune cells, stromal components, and vasculature that interact through complex molecular signaling networks. In cancers driven by oncoviruses, viral infection represents a unique biological factor that profoundly influences TME formation and remodeling, thereby shaping distinct features such as immune evasion, chronic inflammation,...