Mesenchymal stem cells and derived extracellular vesicles in major respiratory diseases: from multifaceted molecular mechanisms to clinical perspectives (opens in new tab)

Mesenchymal stem cells (MSCs), a type of pluripotent stem cells, exhibit remarkable therapeutic properties in the treatment of various diseases. Recent findings on the development of respiratory illnesses indicate that local MSCs might transform into myofibroblasts, thereby resulting in the emergence of respiratory disorders. Nonetheless, both preclinical and clinical studies on autologous or allogeneic MSC infusion reveal that MSCs can mitigate the onset of respiratory disease by controlling...