Frontiers

Traditional Chinese medicine-derived monomers delay osteoarthritis progression by regulating mitochondrial homeostasis (opens in new tab)

Osteoarthritis is a common degenerative disease characterized by the degeneration of articular cartilage, which also affects the synovium, subchondral bone, and the joint microenvironment. Currently, clinical treatment remains focused primarily on pain relief and symptom improvement, with a lack of disease-modifying strategies capable of effectively slowing disease progression. In recent years, the role of mitochondrial homeostasis imbalance in the pathogenesis and progression of osteoarthrit...

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