Extracellular vesicles in bovine reproduction: their journey from gametogenesis to pregnancy (opens in new tab)

Extracellular vesicles (EVs), including exosomes and microvesicles, play a pivotal role in bovine reproduction by mediating communication between gametes, the developing embryo, and the maternal reproductive tract. These vesicles act as carriers of bioactive molecules, such as microRNAs, mRNAs, lipids, and proteins that regulate processes from gametogenesis to early pregnancy. The embryo-maternal dialogue, mediated by EVs, shapes the oviductal and uterine microenvironments, ensuring proper fe...