Essential oil from Artemisia gmelinii extenuates cellular integrity of Sporothrix globosa and its biofilms by steering intracellular ROS and basal ergosterol le... (opens in new tab)

AimSporotrichosis is a fungal zoonotic infection caused by the pathogenic clade of the Sporothrix species complex. Considered a neglected tropical disease, sporotrichosis now has a cosmopolitan distribution through species like Sporothrix globosa. Moreover, multi-drug-resistant S. globosa strains are refractory to conventional antifungal therapy. The present study explores the anti-sporotrichotic effects of the essential oil of Artemisia gmelinii leaves (AgLEO) against a multi-drug-resistant ...