Association between serum 25-hydroxyvitamin D concentrations and overactive bladder in female: a mediation analysis of inflammatory biomarkers (opens in new tab)

BackgroundOveractive bladder (OAB) is a prevalent condition that substantially impairs quality of life. Although 25-hydroxyvitamin D [25(OH)D] plays an important role in immune modulation, its association with OAB and the potential contribution of inflammation remain incompletely understood.MethodsWe analyzed 25,096 participants from National Health and Nutrition Examination Survey (NHANES) 2007–2018 and 2,442 participants from a hospital-based replication cohort (FAH-DMU-DB) using multivaria...