Potential health benefits of bromelain: a critical review of the current literature (opens in new tab)

This review summarizes current knowledge on bromelain, a proteolytic enzyme complex derived from Ananas comosus (pineapple), with a focus on its structure, absorption, metabolism, and therapeutic mechanisms. Bromelain exhibits a wide range of biological activities, including antioxidative, anti-inflammatory, immunomodulatory, antinociceptive, antiulcerative, and antihyperlipidemic effects. These effects are primarily mediated through modulation of key inflammatory and oxidative stress pathway...