A multidimensional platform to support intestinal epithelial and immune cell co-culture (opens in new tab)

IntroductionDetailed research into intestinal immune exposure to luminal contents, including nutrients and microbial metabolites, could be well supported by accurate and reproducible models of the human intestinal milieu. Animal models provide insights but are not fully predictive of human biology, while human correlative studies are hampered by the complexity of feedback signals from established immune reactions. Therefore, characterization of human nutrient uptake and immediate effects on i...