Frontiers

A systematic review and meta-analysis of Vitamin D status and clinical outcomes in critically ill neonates (opens in new tab)

IntroductionVitamin D is key in immunoregulation and impacts critical care outcomes. With a high prevalence of neonatal Vitamin D deficiency (VDD), we aim to evaluate its association with clinical outcomes in the neonatal intensive care unit (NICU).MethodsSystematic search of PubMed, EMBASE, Web of Science and Scopus was conducted. Primary outcomes included mortality and incidence of sepsis, while secondary outcomes were length of stay (LOS), incidence of bronchopulmonary dysplasia (BPD), and...

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