Prognostic impact of low BMI on outcomes following definitive radiotherapy for esophageal squamous cell carcinoma (opens in new tab)

BackgroundEsophageal squamous cell carcinoma (ESCC) is a globally significant malignancy with a poor prognosis. While definitive radiotherapy is a primary curative-intent treatment for early-to-mid-stage ESCC, patient outcomes remain heterogeneous. Nutritional status, as reflected by body mass index (BMI), is increasingly recognized as a critical host-related factor influencing cancer prognosis. However, evidence regarding the impact of low BMI on survival and treatment-related toxicity in ES...