Frontiers

The herbal pair of Smilax glabra Roxb. and Ficus hirta Vahl. improves exercise performance by regulating mitochondrial function via the adiponection receptors-mediated AMPK signaling pathway (opens in new tab)

IntroductionExercise fatigue can significantly impair physical function, while herbal medicines exhibit broad application prospects in anti-fatigue research. The herbal pair of Smilax glabra Roxb. and Ficus hirta Vahl. (FSP) is well-known for its hepatoprotective, dampness-eliminating, and detoxifying effects. However, its mechanism of action in improving exercise performance remains unclear.MethodsThe impact of FSP on exercise performance was assessed through motor behavioral tests and monit...

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