Infant-derived Bifidobacterium strains screened in vitro for alleviating intestinal disorder caused by Escherichia coli (opens in new tab)

IntroductionEscherichia coli (E. coli) is a common foodborne pathogen that can cause various infections such as diarrhea and meningitis.MethodsIn this study, 38 Bifidobacterium strains isolated from healthy breastfed infants were evaluated in vitro. D2, which demonstrated the strongest antagonism against E. coli and the most favorable probiotic properties, was selected for further investigation in vivo. The acid removal experiment of the cell-free supernatant (CFS) of D2 was conducted. Animal...