Nutritional interventions for late-life depression: evidence, mechanisms, and clinical assessment tools (opens in new tab)

Late-life depression (LLD) is common and disabling in older adults, and current pharmacological or invasive treatments are often limited by comorbidity and tolerability. Nutrition is a modifiable target with potential clinical value. This review examines the epidemiological association between nutritional status and LLD. It synthesizes evidence on essential nutrients and dietary patterns, discusses potential underlying mechanisms, and evaluates the clinical utility of nutritional assessment t...