Dietary oxidative balance and renal impairment in diabetes identified by machine learning and functional analysis (opens in new tab)

BackgroundOxidative stress has been implicated in albuminuria-related renal abnormalities in diabetes; however, the combined associations of pro-oxidant and antioxidant dietary components with UACR-defined renal impairment remain unclear. This study aimed to investigate the association between dietary oxidative balance and renal impairment in patients with diabetes and to conduct exploratory in vitro experiments examining whether selected nutrients modulate AKT phosphorylation under high-gluc...