Frontiers

The healthy eating index 2020 and colorectal cancer risk: a prospective study based on the PLCO cohort (opens in new tab)

BackgroundThe Healthy Eating Index (HEI-2020), a metric that assesses overall diet quality based on compliance with the 2020–2025 Dietary Guidelines for Americans, has been insufficiently investigated in relation to both colorectal cancer (CRC) incidence and mortality. To address this gap, we conducted a population-based prospective study of 101,709 U.S. adults from the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial, examining the associations between HEI-2020 adherence...

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