Regulation of inflammation by omega-3 and omega-6 fatty acids: a meta-analysis of randomized trials (opens in new tab)

This study quantitatively compared the anti-inflammatory effects of omega-3 and omega-6 polyunsaturated fatty acids (PUFAs) across different populations via meta-analysis. A systematic search of six major databases identified nine randomized controlled trials (RCTs) involving 504 participants. Data on inflammatory markers, including interleukin-6 (IL-6), C-reactive protein (CRP), interleukin-1 beta (IL-1β), and tumor necrosis factor alpha (TNF-α) were extracted, and subgroup analyses were per...