Associations of novel visceral obesity indices (METS-VF and BRI) with dementia: the role of metabolic mediators and genetic susceptibility (opens in new tab)

BackgroundVisceral obesity-related indices may capture metabolically adverse adiposity more effectively than conventional obesity measures, but their comparative associations with dementia risk and the potential roles of metabolic dysfunction and genetic susceptibility remain insufficiently characterized.MethodsIn this prospective cohort study, 327,368 dementia-free participants from the UK Biobank were included. Body roundness index (BRI) and metabolic score for visceral fat (METS-VF) were f...