Plant-based caloric restriction diets versus conventional calorie-restricted diets for weight loss and metabolic health in obese adults: a 12-week randomized, open-label, non-inferiority trial (opens in new tab)

BackgroundPlant-based caloric restriction diet (PB-CRD), combining plant-based nutrition with intermittent caloric restriction, represent a structured dietary strategy to obesity management. This study compared the effects of PB-CRD and calorie-restricted diet (CRD) on weight loss, and metabolic health, hypothesizing that PB-CRD is non-inferior to CRD for weight loss.MethodsIn this 12-week, open-label, non-inferiority trial, 80 participants with obesity (body mass index [BMI]: 28–40 kg/m2, ag...