Association of the single point insulin sensitivity estimator index with functional outcomes and hemorrhagic transformation in patients with acute ischemic stro... (opens in new tab)

BackgroundInsulin resistance is an important risk factor for adverse prognosis in acute ischemic stroke (AIS). The single point insulin sensitivity estimator (SPISE) index, a novel insulin resistance surrogate independent of fasting plasma glucose, offers a potential advantage for assessing insulin resistance in AIS due to its lower susceptibility to stress-induced hyperglycemia in the acute phase. However, its associations with functional outcomes and intracranial hemorrhagic transformation ...