Comparative assessment of Brassica nigra seed and its sprout ethanolic extracts against paracetamol-induced hepatotoxicity in rats: insight into antioxidant and anti-apoptotic pathways (opens in new tab)

BackgroundThe liver’s central role in xenobiotic metabolism renders it highly susceptible to injury from oxidative stress. Therapeutic drug solutions for liver diseases remain limited. Natural medicinal plants present an option; sprouting is an emerging trend to maximize the plants’ bioactivity. This study explores, for the first time, a direct comparative assessment of the hepatoprotective effects of Brassica nigra (BN) seeds versus their sprout ethanolic extracts against paracetamol-induced...