The long non-coding RNA CidecAS regulates hepatocyte lipid metabolism via the alpha-1 subunit of Na+/K+-ATPase (opens in new tab)

IntroductionThe rising prevalence of metabolic-associated fatty liver disease (MAFLD) poses a serious public health threat, while long non-coding RNAs, key regulators of hepatic lipid metabolism, are closely linked to its development and progression. This study identified a novel MAFLD-associated antisense lncRNA, lnc-CidecAS, aiming to characterize its molecular structure and elucidate its regulatory role in hepatic lipid metabolism.MethodsThe sequence characteristics and coding potential of...